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The duration varies based on the deficiency cause, symptom severity, and patient response

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Am J Physiol Endocrinol Metab 301(3):E560E565 Nieman KM, Rowling MJ, Garrow TA, Schalinske KL (2004) Modulation of methyl group metabolism by streptozotocin-induced diabetes and all-trans-retinoic acid

It is important to note that drugs like NSAIDs and steroids can have long-term detrimental effects on knee OA, accelerating degeneration