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Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics of gliclazide MR in Chinese subjects

Heart rate was highest when tobacco was combined with cannabis, while there was a moderate increase in blood pressure among participants who combined the drugs, which the researchers say could add to the cardiovascular risk of smoking cannabis

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[17] While the FTC has always recognized that the smoking machine cannot accurately replicate human smoking and that no two human smokers smoke in the same way, the FTC did not initially recognize the tobacco industry's ability to design cigarettes that yielded low levels of tar and nicotine when machine-smoked, but yielded much higher levels when smoked by a human being