Treatment with 5-amino-1mq upregulates proliferationrelated genes (Ki67, PCNA), promotes cell cycle progression, and improves cell fusion efficiency to form more multinucleated myotubes, achieving functional levels similar to those of young mice.Additionally, 5-amino-1mq inhibits muscle stem cell apoptosis, reduces oxidative stress damage, and maintains stemness
As the transport of substrates and drugs by MRP1 relies on unclear relationships with GSH binding and transport 9,10 , we looked at the ability of the different chimeras to confer a MDR phenotype in a GSH-dependent manner
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Contributes to integrated sleepstressendocrine research frameworks: Sleep quality, stress response, and hormonal balance are interdependent biological systems
& Ebrahimian, M
