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Many patients stop treatment prematurely due to side effects that could have been managed with the right support and education

When you see how many systems are involved brain, hormones, immune cells, metabolism it becomes clear this is a complex disease, he said

For example, 15% of 106 females between the ages of 16 and 42 years had genital nevi, and in a study of 100 random autopsies, three cases showed melanosis of the genitalia, and all three were elderly women

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