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In subjects with cardio-metabolic conditions, the accumulation and function of fat deposits (including EAT) is deregulated [89]

Neither drug is FDA approved for weight loss

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Any concurrent use should only occur under specialist supervision such as an endocrinologist with regular monitoring of hormone levels, haematocrit, and cardiovascular markers

While you may recognise these active ingredients from diabetes treatments, they are prescribed under specific names when used for weight health

Hunger typically peaks two to three weeks after stopping and then stabilizes as the body recalibrates energy homeostasis