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Toxicol Appl Pharmacol 2007;220:14655

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Este esquema reconoce tres vas adicionales que generan hiperglucemia: cambios en la microbiota intestinal, reduccin en la produccin de amilina por la alteracin de la clula beta (vaciamiento gstrico acelerado con aumento en la absorcin de glucosa en el intestino y aumento de la glucemia posprandial) y un estado inflamatorio que genera aumento en la demanda de insulina, todos ellos tericamente cubiertos con los AGLP1