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doi: 10.12688/f1000research.73470.2 98

When combined in research applications, these peptides demonstrate complementary mechanisms that create a sustained, pulsatile growth hormone release pattern more closely mimicking natural physiological rhythms than either peptide alone

BDHI probes labeled proteins to a much lesser extent compared to promiscuous iodoacetamide probe and required a relatively higher concentration, likely due to low or slow reactivity of the BDHI electrophile towards target proteins with a non-optimal binding element

For ipamorelin, the recontextualization mattered

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