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278, 1364013646 Received for publication March 9, 2009

In recent years there has been considerable interest in the therapeutic potential of l-carnitine and its acetylated derivative acetyl-l-carnitine (ALCAR) for neuroprotection in a number of disorders including hypoxia-ischemia, traumatic brain injury, Alzheimers disease and in conditions leading to central or peripheral nervous system injury

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This has led to conceptualizing obesity as a chronic disease requiring ongoing management rather than a condition amenable to short-term cure

Elaines stories explore the boom in new obesity treatments, new drug payment models, the ways companies are affected by FDA changes, and the emerging psychedelics drug sector