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Hormonal Disruption & Early Menopause Smoking may lead to early menopause , compounding sexual dysfunction and fertility issues

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Another meta-analysis examined 15 observational studies (6 cohort and 9 case-control) including 17,890 ASD cases and 1,810,258 controls/participants to explore whether an association exist between maternal smoking during pregnancy and ASD risk in offspring [118]

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Contraception and aging Nowadays, using contraceptive methods in different countries and cultures has increased the age of childbearing in both men and women