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GLP-1s can be used to treat chronic weight management, especially for those living with obesity or who are overweight
As for why Novo would allow its patents to expire, a spokesperson told CNBC that all intellectual property decisions are "carefully considered," and that "periods of exclusivity for pharmaceutical products end as part of their normal life cycle and generic treatments may become available over time." Novo lost its Canadian patent after its lawyers requested a refund for the 2017 patent maintenance fee because the company wanted more time to see if it wanted to pay the required $185
After the exclusion of 9,075 patients due to prior anti-obesity medication, and 72,731 patients for bipolar, schizophrenia, depressive disorders, anxiety and suicide ideation or attempts within 1 year before, the treatment cohort numbered 162,257 patients
NNMT is a very important component in metabolism and energy and is predominantly active in fat tissue
Recent clinical trials have demonstrated that GLP-1RAs have beneficial effects on renal outcomes, especially in patients with T2D who are at high risk for CVD
