Just had my vitamin B12 injection
A large, prospective, population-based cohort study in China (N = 567,071 couples) observed that folic acid supplementation started three months prior to conception may reduce the risk of NTDs (OR = 0.55, CI: 0.39-0.82, p=0.003) and clefts (OR = 0.59, 95% CI: 0.36-0.95, p=0.029 (54)
It contains a cyano (cyanide) group in its structure, which makes it more stable than other forms of vitamin B12 as the cyanide stabilizes the molecule from deterioration
So the practical takeaway is not oral is better or SC is better. It is: pick one route, follow the documented per-dose figure for the vial you have, and keep the route constant so that whatever you observe is not confounded by a mid-stream route change
And unless you have low vitamin B-12 levels in your body, vitamin B-12 shots arent likely to give you more energy or improve your performance
A molecule that is not what its label claims is not simply ineffective, it is a genuine safety concern, because you cannot know what you are actually putting into your body