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The systemic iron-regulatory hormone is hepatic peptide hepcidin 36

It is critical for the maintenance of antioxidative balance by helping to protect cells from oxidative stress

The lipid barrier consists of ceramides, fatty acids, and cholesterol that form protective layers between skin cells

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In this context, a proposal is presented on the possible sequence of events that could be involved in the development of these diseases, focusing on the interaction between immune hyperactivation, autoimmune hypophysitis or pituitary hypophysitis and immune depletion

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