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* Correspondence: Damjan Osredkar [email protected] ORCID Damjan Osredkar orcid.org/0000-0002-2188-420X Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

At the molecular level, TCM-mediated HDAC modulation converges on key deacetylation substrates, including transcription factors (NF-B p65, AP-1, STAT3, NLRP3, HMGB1, HIF-1) and histone H3, with collective effects in attenuating RA-related inflammation, synovial angiogenesis, and metabolic dysregulation

Scrimshaw NS, SanGiovanni JP

There was an effective reduction in systolic BP in both young and aged rats [95]

The vaccine is stored in the dark at +2/8C