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Bioactivation of nephrotoxic cysteine S-conjugates in mitochondrial outer membrane

Germain et al., 2017

A., Valetdinova, K

Astaxanthin reduces the expression of FN, ICAM-1, and TGF-1 induced by HG to reduce ECM deposition, and significantly promotes the nuclear translocation and transcriptional activity of Nrf2, and induction the expression of HO-1 [149, 150]

This ensures you aren't just "expensive-flushing" your supplements, but actually providing your cells with the nutrients they require