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On the other hand, at low levels, cadaverine is imported to the cytoplasm of macrophages by L-lysine transporters, inducing a modest increase in glycolysis that supports Oxphos and itaconate generation

Moving toward a systems-level understanding, empowered by interactomics, CRISPR technologies, AI-driven modeling and precision biomarker science, will profoundly transform how we interpret disease biology and develop therapeutics

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Evidence shows that c-Myb is involved in ferroptosis through a cysteine dioxygenase 1 (CDO1)GPX4 axis