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Hopes also were high that the medications might help people at risk for Alzheimers, but so far, that research has not panned out

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3.2.1 Limitations of current AD treatments and the need for new approaches Despite continuous advancements in AD drug development, currently available treatments do not effectively halt or reverse disease progression

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The expression of target genes was analyzed via quantitative real-time (RT) PCR with a QuantaStudio 5 qPCR machine (Applied Biosystems, Thermo Fisher Scientific)