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It is hypothesized that the primary role of increasing primary corticotropin-releasing hormone (CRH) might be a more direct driver of hair loss in AA as demonstrated by experimental work (Zhang et al
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However, the immune response of the CNS is complex and involves a myriad of diverse cell populations such as astrocytes, microglia, macrophages, NK cells, and T and B cells ( Current GSH treatment for neurodegenerative disorders has been focused largely on trying to bypass the BBB (Liu et al., 2017)
Dghim et al., In contrast to GSSG reduction, the reactions that are most important in converting GSH to GSSG are less clear and, potentially, more complex
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