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Glutathione may also help manage symptoms of autoimmune diseases and psoriasis by reducing oxidative stress and inflammation

Combining these could potentially produce additive anti-inflammatory effects, which might be beneficial or could result in excessive immune suppression depending on the context

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A separate set of enzymes and transporters also plays a buffering role by eliminating acetyl-CoA from inside mitochondria created by the pyruvate dehydrogenase complex that is in excess of its utilization by the Krebs cycle