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Barzaghi, N., Crema, F., Gatti, G., Pifferi, G., & Perucca, E

The availability of arginine and endogenous or pharmacological analogs of arginine can constrain NO synthesis

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Results for Study 1 and Study 2 The proportions of patients who discontinued study drug in Study 1 were 14.3%, 16.4%, and 15.1% for the 5 mg, 10 mg, and 15 mg ZEPBOUND-treated groups, respectively, and 26.4% for the placebo-treated group

Cellular metabolism is reprogrammed to meet the increase in bioenergetic and biosynthetic demands associated with effector T cell expansion