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The mTOR pathway, serving as a critical metabolic regulator and mitophagy gatekeeper, integrates both metabolic and inflammatory signals to calibrate mitochondrial turnover and ROS productionkey mediators of ferroptosis induction by Erastin (6365)
Oxidized glutathione bound to arsenic (purple), a human carcinogen (Rubino, 2015)
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Erdoan MA, Tun KC, Datan A, Tomruk C, Uyankgil Y, Erba O
Cardiovascular complications of diabetes: from microvascular to macrovascular pathways