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Endogenous and exogenous reactive oxygen species, such as superoxide anion, hydroxyl radical, hypohalite radical, and hydrogen peroxide, and reactive nitrogen species, such as nitric oxide, peroxynitrite, and nitrite, play a major role in the airway inflammation and are determinants of asthma severity

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Glutathione (GSH) is the most abundant endogenous antioxidant in the human body a tripeptide of cysteine, glycine, and glutamic acid, synthesised primarily in the liver and present in every cell