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In most mammals, melanin formation consists of eumelanin (brown-black pigment) and pheomelanin ( yellow-red pigment) as either mixtures or copolymers

Extraction of intracellular metabolites, GC-MS measurement, MID calculations, determinations of fractional carbon contributions, and subtractions of natural isotope abundance were performed as described 44

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Table 1 Efficacy of GLP-1 agonists efficacy (adapted from UpToDate) ( GLP-1, glucagon-like peptide 1

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Little, University of Louisville, United States Reviewed by Oscar Lorenzo, Health Research Institute Foundation Jimenez Diaz (IIS-FJD), Spain