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Once reconstituted, solutions should be immediately aliquoted into single-use volumes and stored at -20C, protected from reducing agents, which can cleave the critical disulfide bond

Similarly, earlier studies led by Sikiric and colleagues in the 1990s suggested safety and benefit in gastrointestinal conditions such as ulcerative colitis, but these reports were published only in abstracts or local conference proceedings, with no independent replication or peer-reviewed validation

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