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Results GLP-1 RAs significantly reduced the risk of composite outcomes at one year (Hazard Ratio, HR 0.784

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95% CI, 0.57 to 0.85) and 50% (HR, 0.56

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For BPC-157 specifically, the FDA reported limited and short human studies, a lack of adequate studies for several commonly used routes of administration, potential immunogenicity concerns, possible liver and clotting signals in animal studies, and three adverse-event reports, while noting that a cause could not be established

In an audience packed with senior R&D leadersincluding over 10 from Eli Lilly, alongside key figures from Novo Nordisk, AstraZeneca, Roche, Boehringer Ingelheim, and others the realization dawned that a traditional pharma giant had officially evolved into the first longevity pharma company