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To explore the functional relevance of these DEGs, gene ontology (GO) enrichment analysis was conducted, revealing that the altered genes were primarily involved in immune response regulation, cytokine production, oxidative stress response, and mitochondrial functions

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This glutamate is then further catalyzed to -ketoglutarate via deamination mediated by glutamate dehydrogenase (GLUD1) or transamination mediated by transaminases [331]