Both loop diuretics and thiazide diuretics are also known to cause potassium wasting, so concurrent therapy with corticosteroids may be additive
The 2.0 mg dose is typically reserved for patients who: Have not achieved adequate blood sugar control at lower doses Require additional weight management support Can tolerate the medication without severe side effects Need further weight reduction beyond what lower doses provide While Ozempic is FDA-approved for type 2 diabetes and cardiovascular risk reduction, many healthcare providers prescribe it off-label for weight management in patients with a body mass index (BMI) of 30 or higher, or 27 or higher with weight-related health conditions
That said, there are a few downsides: High cost: GLP-1 drugs can run over $1,000 per month if not covered by insurance
May help improve energy levels
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Current Market Pricing (Without Insurance) For context, currently available medications in Canada cost approximately: Wegovy (Semaglutide): $450-550 CAD per month Mounjaro/Zepbound (Tirzepatide): $400-500 CAD per month Saxenda (Liraglutide): $500-600 CAD per month Expected Retatrutide Pricing Eli Lilly typically prices competitively
