Novo Nordisks semaglutide (Ozempic and Wegovy) and Eli Lillys tirzepatide (Mounjaro and Zepbound) have become the poster children of this revolution, showcasing weight loss that was previously unattainable with pharmaceutical interventions alone
Previously, coverage was limited to people taking GLP-1s for conditions such as diabetes or cardiovascular disease
Lancet 377:19291937 Creager MA, Olin JW, Belch JJ, Moneta GL, Henry TD, Rajagopalan S, Annex BH, Hiatt WR (2011) Effect of hypoxia-inducible factor-1alpha gene therapy on walking performance in patients with intermittent claudication
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RNA was resuspended in nuclease free water and stored at 80 C
Smaller, more frequent meals may be better tolerated than large meals