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Hippocampal neurons transfected with mRFP-p-actin were treated with 10 ' 2 M dihexa or 10 "12 M Nle'-Ang IV for 5 days or 30 minutes in culture prior to fixation on day in vitro 12 (DIV12)

Consistent with human observations, H2O2 also promoted FOXO4 nuclear translocation in TM3 cells, along with an increase in senescence markers p53, phospho-p53, and p21, while reducing testosterone synthesis-related enzymes like CYP11A1 and CYP17A1

Mood Regulation : B12 is involved in producing brain chemicals that regulate mood and mental function

*These authors jointly supervised this work