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This results in a blockade of IGF-1 beneficial actions [124, 126, 127]

But the reality is that for most of human history, having enough food or even any food at all was often far from a sure thing

In 2024, a study by Schmitt et al., involving a significantly larger cohort of 2023 participants, confirmed that smokers ( n = 418) exhibited higher levels of circulating eryptotic erythrocytes compared to non-smokers ( n = 1000) and ex-smokers ( n = 605) [441]

However, a long list of factors among them poor sleep, chronic stress and ultra-processed foods act to suppress your natural GLP-1 production and function, making it harder for your body to regulate weight on its own

While research is still ongoing, early findings and anecdotal reports are generating excitement in the wellness community

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