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Laboratory protocols explore how senescent T cells, B cells, and other immune cells contribute to age-related immune dysfunction, while FOXO4-DRI administration provides researchers with methods for testing immune system restoration following senescent cell elimination

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In 2019, liver-expressed antimicrobial peptide (LEAP2), initially discovered as an antimicrobial peptide produced in the liver, was identified to be upregulated in the stomach of diet-induced obese mice after vertical sleeve gastrectomy

These findings suggest that alterations in the excitatory neurotransmission regulation, presumably increased cycling of the Gln-Glu circuit, may underlie the pathophysiology of ASD