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Exenatide did not work in cocaine use disorder, but it did reduce drinking in obese patients with alcohol use disorder (Klausen MK et al, JCI Insight 2022;7(19):e159863)

And patience beats dose increases almost every time

"The identity of glutathione S -transferase B with ligandin, a major binding protein of liver"

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Reformer Pilates involves doing pilates moves on special machines and reportedly improves posture, flexibility and balance

Implications from the study were that GLP-1 is associated with a higher risk of NAION but that further studies are required to determine causality