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Although astrocytes can utilize fatty acids as an alternative energy source, prolonged reliance on lipid oxidation results in oxidative stress and mitochondrial impairment, exacerbating neurodegeneration 82

So, Weinberg et al hypothesized that overloading cells with exogenous fatty acids by infusing a lipid emulsion would exacerbate LA toxicity

GLP-1 receptors are expressed in many peripheral tissues including the and cells of the pancreas, heart, lungs, kidneys, gastrointestinal tract as well as both the central and peripheral nervous systems 8

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The supernatant was dried under nitrogen at 60 C, then cooled