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"I'm probably overall very skeptical, but I'm happy to be proven wrong." The potential cost of the implant and whether insurers would cover it if approved also remain unclear

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Reliable imaging tools such as magnetic resonance spectroscopy (MRS) now allow real-time measurement of brain GSH levels, facilitating early detection and therapeutic monitoring

[41] The major limitation is teratogenicity from topiramate, especially risk of oral clefts with fetal exposure