By activating both GIP and GLP-1 receptors, tirzepatide enhances glucose-dependent insulin secretion from pancreatic beta cells, suppresses inappropriate glucagon release, and slows gastric emptying
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Discontinuing tirzepatide without a medical plan can lead to a return of previous symptoms or health issues, so we generally recommend continuing the medication as directed to sustain its benefits
Tirzepatide is not recommended during pregnancy, and women of childbearing potential should use effective contraception
Overweight Individuals: People with a BMI of 27 or higher, especially if they also have weight-related conditions like high blood pressure, type 2 diabetes, or high cholesterol