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Because of this, the Alzheimers Drug Discovery Foundation has dubbed it the most well-validated form of urolithin A4 This isnt to say other forms of urolithin A cant be beneficial, but we do hope to see more research on non-Mitopure urolithin A in the future

Receptor Mosaic (RM) A2A-mGlu5-D2 RM A2AR and mGlu5 act synergistically to counteract the D2R signaling in striatopallidal neurons, reducing mGlu5 desensitization (79), and exciting the striatopallidal GABA neurons with firing and altered gene expression (80, 81)

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It's also loaded with fatty acids (mostly linoleic (50-74%) and oleic (14-35%))

Ischemic stroke and intestinal flora: an insight into brain-gut axis