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By increasing and prolonging active incretin levels, sitagliptin increases insulin release and decreases glucagon levels in the circulation in a glucose-dependent manner

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Multiple Medication Question Before moving to insulin, I want to address a question that deserves explicit attention: why are patients so often on multiple medications for the same condition

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Furthermore, it inhibits the osteoclastic differentiation involved in the regulation of bone metabolism and remodeling and possesses anti-osteoporotic effects (Ming et al., 2016