side effects of semaglutide oral for diabetes and obesity treatment Best GLP-1 for Weight Loss:

These include gallbladder and kidney problems, Low Blood Sugar or Hypoglycemia, Diabetic Retinopathy and Pancreatitis

Pujadas, G

Idiopathic intracranial hypertension

Gastrointestinal symptoms dominate the side effect profile: Nausea: The most commonly reported side effect, particularly during dose escalation

It is well established that patients with diabetes demonstrate higher susceptibility to pancreatic cancer and pancreatitis compared to non-diabetic individuals, and theoretically, sustained GLP-1 receptor activation induced by GLP-1RA therapy may potentially elevate pancreatic cancer risk [8]

From a broader immunologic perspective, Karacabeyli and Lacaille 1 note that GLP-1 RAs may influence shared inflammatory pathways involved in immune-mediated inflammatory diseases (IMIDs), including psoriasis and inflammatory arthritis