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These changes are especially important to note given the direct and indirect effects of alterations in claudin-1 transgenic mice of normal colonocyte differentiation program, and mucin-2 expression in a matrix metalloproteinase-9/Notch-dependent manner (Figure 2)

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Unfortunately, lactase-deficient individuals cannot digest milks main carbohydrate, lactose, depriving themselves of highly beneficial milk proteins like casein, lactoalbumin, and lactoglobulin due to lactose intolerance (LI), while other individuals develop allergies specifically against these proteins (CMPA)

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In addition to its role in ATP synthesis, mitochondrial coenzyme Q 10 mediates the oxidation of dihydroorotate to orotate in the de novo pyrimidine synthesis

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