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They signal fibroblasts to make more collagen and elastin

Thomas DN, Wills JW, Tracey H et al (2024) Ames test study designs for nitrosamine mutagenicity testing: qualitative and quantitative analysis of key assay parameters

Geoscientific Model Development, 7 , 12471250

Materials and methodsSubjects of study A prospective cross-sectional study was conducted recruiting women patients with newly diagnosed Graves disease (n=18), patients with Graves disease treated with methimazole for more than two months (n=6) and healthy euthyroid individuals (n=15)

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The conversion of NTPs to dNTPs is catalyzed by ribonucleotide reductase (RNR), a heterodimer of RRM1 and RRM2 or RRM2B subunits