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If standardized peptide formulations can be verified and administered within controlled protocols, these agents may represent a future adjunct to evidence-based perioperative care, particularly in populations undergoing TJA where wound healing, metabolic health, and inflammatory regulation strongly influence outcomes

The exclusion criteria were as follows: pregnancy, lactation, menopause

Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues

Palmitoylethanolamide (PEA) is an 18-carbon long- chain fatty acid

Vasoactive Intestinal Peptide Synergizes With TNF- in Inducing Human Dendritic Cell Maturation