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[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Folli F., Finzi G., Manfrini R., Galli A., Casiraghi F., Centofanti L., Berra C., Fiorina P., Davalli A., La Rosa S., et al

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On the positive side, GLP1-S has demonstrated cardiovascular benefits in large outcome trials, with evidence suggesting a reduction in the risk of major adverse cardiovascular events in participants with type 2 diabetes

It inhibits inflammasome activation (e.g., NLRP3) and ACE activity, modulates mitochondrial function, and regulates -adrenergic signaling, effectively reducing oxidative stress, vascular inflammation, and cardiac remodeling [80]

doi: 10.1177/0883073808321060 20

This mechanism doesn't worsen celiac-related inflammation or increase nutrient malabsorption