Weeks 16 through 24 and beyond: maintenance phase If the combination has been well-tolerated through the titration phase, maintenance involves continuing both compounds at their established doses while reducing bloodwork frequency to monthly
In a recent study published in the Journal of Clinical Investigation , researchers reviewed the anti-inflammatory effects and mechanisms of glucagon-like peptide 1 (GLP-1)-based therapies
Retatrutide has the potential to enhance weight reduction outcomes and manage obesity-related comorbidities like diabetes and hypertension (high blood pressure) when paired with a healthy diet, consistent exercise, and lifestyle adjustments
WangMDHuangYZhangGPMaoLXiaYPMeiYWet al
In March 2026, the first phase III clinical study (HS-20094-301) of olepotide in overweight or obese adult subjects in China achieved its primary endpoint
You feel more in control of your appetite, and your weight loss efforts are paying off