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Mechanisms of vascular injury due to smoking Patients with PAD have disrupted blood flow to the limbs due to the formation of atherosclerotic plaque and the development of atherothrombosis

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For example, as part of the Marlboro Fresh product line, Marlboro Black Menthol was launched in Japan during 2008, and soon thereafter offered in several additional markets, including Indonesia and the Philippines.1 According to PMIs 2008 annual report, Marlboro Black Menthol was launched to deliver a cigarette with a bold, long-lasting, high-cooling sensation in a striking black pack

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