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The dosing protocols differ significantly between the two medications, with tirzepatide starting at 2.5 mg weekly and potentially escalating to 15 mg based on tolerance and response

Fonseca V.A., Devries J.H., Henry R.R., Donsmark M., Thomsen H.F., Plutzky J

While tirzepatide reduces appetite, maintaining adequate caloric intake supports metabolic function

Dimorphic cardiac adaptation to obesity and arterial hypertension

J Clin Pharmacol 46(10):11791187 Steinert RE, Meyer-Gerspach AC, Beglinger C (2012) The role of the stomach in the control of appetite and the secretion of satiation peptides

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