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The retatrutide Phase 2 obesity trial , published in the New England Journal of Medicine, demonstrated weight loss of up to 24.2% at the 12mg dose after just 48 weeks

"Upon achieving your target weight, our team will collaborate with you to determine the optimal treatment strategy for transitioning to a weight maintenance phase

Understanding how these symptoms align with dose escalation is essential for optimizing adherence and minimizing treatment interruptions

Both drugs, particularly higher doses of tirzepatide, increased gastrointestinal adverse events

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