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Current availability is limited due to supply constraints and budgetary considerations

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The recommended daily allowance (RDA) for vitamin B12 for most adults is 2.4 micrograms (mcg)

The maximum duration of any of the few studies in which a good technique has been used to quantify emptying (usually scintigraphy) is 16 weeks, and while the magnitude of the delay in emptying at that time point was not as marked as at 5 weeks, it was substantial in some cases (47)