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Increased constipation risk Constipation affects around 24% of people taking Wegovy, making it one of the most common and persistent side effects in clinical trials

5 Together, SNAC-enabled peptide delivery and small-molecule agonists have the potential to expand access to incretin therapy by improving stability in the stomach, enhancing epithelial transport, and simplifying real-world use

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Five mechanistic axes are documented: 1

1 One randomized, controlled trial compared the efficacy of topiramate 75 mg to placebo in treating adolescents aged 12 to 18 years with severe obesity

Its flexibility without food or water restrictions suits busy schedules, making it an orally active GLP-1 agonist