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After the reaction was completed, a blocking solution consisting of 65 ml methanol and 47 ml DIPEA was added into the reaction column for another 30 min

In rats, intravenous infusion of GLP-1 (7-37amide) or exendin-4 acutely increases HR as well as systolic, diastolic, and mean arterial BP (Figure 7) [634,635]

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