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Kumar C, Sharma R, Bacchawat AK (2003) Investigations into the polymorphisms at the ECM38 locus of two widely used Saccharomyces cerevisiae S288C strains, YPH499 and BY4742

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This attrition is what scientists call the Hayflick limit, named after Leonard Hayflick, who discovered that normal human cells divide roughly 4060 times before stopping [23]