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Zofran, while generally considered safe, can cause headaches, dizziness, and constipation in some people

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However, this mechanism could potentially increase the risk of pulmonary aspiration during anaesthesia

According to the FDA Prescribing Information, if you know you'll be unavailable on your usual injection day, you can adjust your schedule by administering the dose up to three days before or after your regular day, then continuing weekly from that new day

The trials evaluated a higher weekly maintenance dose for people who do not meet goals on the approved dose